Findings. We describe an unusual case, not yet described in literature, of a patient who reported migraine remission, but still presented aura attacks, since starting a therapy with Warfarin. How to use Coumadin. Read the Medication Guide provided by your pharmacist before you start taking warfarin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. I was put on Warfarin (Coumadin) but was not given any warning about alcohol and at least on 2 occasions drank quite heavily (about 5 or 6 glasses of wine in one evening). Headaches!.I have been getting more and more headaches and they are beginning to alarm me.I have mentioned this to the anticoagulant clinc that I go to and they assured me that headaches are only a side effect as ones body adjust to coumadin. I'm 28 and have been taking warfarin all year due to brain clots caused by another medication's side effects. I was on it for five to six months before the headaches started. I have been taking this coumadin for over a year and at any given time I get a headache I just want to know what can I do for it. I had a dvt in my left leg in May and I have been on Coumadin ever since. I have had a whopper of a headache since last week and it seems to be getting worse instead of better. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Simon on coumadin and headaches: Not sure what meds. U r taking, but please review with the prescribing doctors. Hi, Thanks for writing in. It is very difficult to tell what has caused the change in intensity of your headaches. I would suggest you to consult your physician about it because Coumadin can also cause headaches which are usually sudden and can indicate internal hemorrhage. I started taking Warfarin 3 weeks ago after my PVI ablation. Since my first dose, I've been experiencing headaches almost every day. I rarely get headaches (maybe one or two a year) so it is significant to have them every day.