Estradiol is a medication that contains a form of the hormone estrogen. This is a very powerful hormone, and using topical or oral forms can cause serious side effects, including an increased risk of heart attack, blood clots, endometrial cancer, and breast cancer. Bioidentical estradiol in pill form is converted in the liver to estrone, a weaker bioidentical estrogen. But given in a patch, it enters the bloodstream as bioidentical estradiol. My husband and I have only been trying to conceive since November, and I also turned 35 that same month. I realize that pregnancy doesn't always happen right away despite temperature tracking & ovulation tests etc., but I've begun to get nervous recently that I won't be able to get pregnant. Prometrium (progesterone, USP) Capsules contain micronized progesterone for oral administration. Progesterone has a molecular weight of 314.47 and a molecular formula of C 21 H 30 O 2. PROMETRIUM (progesterone, USP) Capsules contain micronized progesterone for oral administration. Progesterone has a molecular weight of 314.47 and an empirical formula of C 21 H 30 O 2. Print and Share (PDF 3357 KB) Menopause (sometimes called “the change of life”) is a normal time in a woman’s life when her period stops. I've been having really bad night sweats since before my periods stopped. Estrogen therapy didn't help - now I'm in menopause, what can I take to get a good night's sleep? DESCRIPTION. PROMETRIUM (progesterone, USP) Capsules contain micronized progesterone for oral administration. Progesterone has a molecular weight of 314.47 and a molecular formula of C 21 H 30 O 2. Find a comprehensive guide to possible side effects including common and rare side effects when taking Estraderm (Estradiol Transdermal) for healthcare professionals and consumers. Should you use Progesterone Cream? Why is progesterone so important? One of the most important reasons is that Progesterone helps to regulate and balance estradiol (2) in the female body.