Effexor and Weight Loss/Gain Jenlynne. Has anyone taken Effexor and, if so, did you experience any weight related side-effects. Omg I& 39;m going through the same thing. Water retention. Weight gain of 10 pounds in 2 weeks, Comment. sho1402. I was on effexor for appx. 5yrs. I am a 35 yr old male. I came off 250mg cold turkey. I had a hard week and a half, but after that things got better. In the case of Effexor XR, an antidepressant, weight change is one of the anticipated side effects. According to an FDA clinical trial, 7 percent of people with depression who were treated with the medication experienced a weight loss of 5 percent or more. Weight gain is not listed as a side effect, however changes in appetite or weight is listed: Two aspects; depending on your metabolism, it can either increase your appetite therefore the weight gain or the contrary depending on how you organism reacts to Effexor. Effexor can affect the weight and cause weight gain. But it is temporary effect, that goes away within few weeks. Other typical side effects are headache, sweating, sleepiness, nausea and dry mouth. Before starting Effexor I weighed 145lbs then 130lbs I lost weight no matter what I ate. Never thought I would gain weight. Well I started feeling better and I would eat. I have gained weight and I feel GREAT. I'm still able 2 exercise and thank God I have gained weight. Everybody reacts different with medication. Effexor has been a miracle medication 4 me. Find for discount Effexor Xr Weight Loss check price now. on-line searching has currently gone a protracted manner; it's modified the way customers and entrepreneurs do business these days. Venlafaxine, formerly sold as Effexor, is a prescription drug used to treat depression, anxiety, social phobia, and panic disorder. The brand name Effexor has been discontinued in the United. Effexor and weight loss. Surprisingly there are individuals who report losing weight while taking Effexor (venlafaxine). The reason for this may be that some medications can have drastically different effects on different individuals due to differences in body chemistry. Check price for Effexor Xr Weight Loss get it to day. on-line shopping has currently gone a long means; it's modified the way consumers and entrepreneurs do business today.