The most common (≥ 2% more frequent than low-dose 50 mg/day TOPAMAX ®) adverse reactions causing discontinuation were difficulty with memory, fatigue, asthenia, insomnia, somnolence, and paresthesia. Yes, diabetes can cause frequent urination, and diabetes can be caused by seroquel. I also *think* I've read somewhere about frequent urination and psych meds. Frequent Urination is a known side effect of Topamax. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. - Page 3 Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. nausea drowsiness weakness or tiredness excitement or anxiety nightmares dry mouth skin more sensitive to sunlight than usual changes in appetite or weight constipation difficulty urinating frequent urination blurred vision changes in sex drive or ability excessive sweating Zofran-Ondansetron may cause side effects. Hello Vicki Jane You are correct Topamax can cause frequent urination. It is one of the rarer side effects of this medication. Take care. Find information about common, infrequent and rare side effects of Topamax Oral. Frequent Urination Another problem in the bladder caused rarely by Topamax is the frequent need to urinate. This means you still have bladder control, but need frequent trips to the bathroom. Frequent urination has been reported by people with high blood cholesterol, generalized anxiety disorder, gastroesophageal reflux disease, attention deficit hyperactivity disorder, pain (latest reports from 822 Frequent urination patients). Topamax (generic name: topiramate) is part of a family of medication known as anticonvulsants. It is used to treat and prevent seizures in adults and children. For the Consumer. Applies to topiramate: oral capsule, oral capsule extended release, oral tablet. Along with its needed effects, topiramate (the active ingredient contained in Topamax) may cause some unwanted effects.