Plavix doesn’t cause nosebleeds, but it does prevent your body from forming blood clots like it usually does. This means that when you have bleeding, including nosebleeds, your body isn’t able. [11-06-2015] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death. Find patient medical information for Plavix oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. What Is Plavix? Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular disease and some stroke (ischemic type) patients. Plavix is available in generic form. Plavix, also known by its scientific name clopidogrel, was first approved by the Food and Drug Administration (FDA) in 1997. The drug is a blood thinner used to reduce the risk of blood clots. Plavix may also be used for purposes not listed in this medication guide. Warnings. Plavix keeps your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions. Because of this drug action, Plavix can make it easier for you to bleed, even from a minor injury. Does Plavix interact with other medications? Should I avoid certain foods while taking Plavix? What should I know regarding pregnancy, nursing and administering Plavix to children or the elderly? How long does Plavix stay in the body once I stop taking it? Plavix is estimated to be cleared from your body in about 33 hours. A single, oral dose of Plavix (clopidogrel) 75 mg has a half-life of approximately 6 hours. It takes 5.5 x half-life of a medicine for a drug to leave the body, therefore most of the Plavix should be eliminated from your system in 5.5 x 6 = 33 hours. Elimination. Back on Plavix and the shortness of breath is back. I don’t know why the doctors insist Plavix does not cause shortness of breath. Reply. thomas says. May 21, 2018 at 3:13 am. Blood problem developed 6 weeks after DES and plavix. Hemoglobin dropped to 5.1, then 4 blood transfusions over 2 weeks. Off plavix after 7 weeks, back on baby aspirin instead. Hematologist told it was ‘recent. Plavix (generic: clopidogrel bisulfate) is an anti-platelet blood clotting prevention drug used to prevent heart attacks and strokes, and to treat peripheral vascular disease and claudication. Learn Plavix side effects, dosage, and more.