CDC - Public Health Media Library. For-non technical or general public health questions, contact CDC-INFO by phone 800-CDC-INFO (800-232-4636) or email. No, acetaminophen (Tylenol) is not classified as an NSAID (nonsteroidal anti-inflammatory drug). Acetaminophen is classified as a miscellaneous analgesic for mild to moderate pain and fever. It is hypothesized that acetaminophen may inhibit COX enzymes, similar to the way NSAIDs work, but without the anti-inflammatory component. No, Tylenol (acetaminophen) is not an anti-inflammatory. Tylenol is classified as a painkiller for mild to moderate pain and fever. There is a theory that acetaminophen may inhibit COX enzymes, similar to the way NSAIDs work, but without the anti-inflammatory effect. Tylenol typically has a lower effect on pain due to inflammation than NSAIDs. Comments. On October 19, 2021 at 10:19 pm, George 1 said: Of course the timing of this medical advice concerning Aspirin is just a coincidence. On October 19, 2021 at 11:21 pm, BRVTVS said: Not only that, but pulling baby aspirin off the market for pediatric use in the 80s meant that most parents now use tylenol.