Nausea, headache and a dry mouth are among the most common side effects of Cymbalta. In rare cases, patients have suffered serious — and sometimes fatal — side effects, including liver damage, abnormal bleeding, and suicidal thoughts and behaviors. Learn about Cymbalta (Duloxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Cymbalta official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Cymbalta is an antidepressant approved to treat mood and pain disorders. It was one of Eli Lilly’s most profitable drugs. It works by preventing the body from reabsorbing two neurotransmitters: serotonin and norepinephrine. Cymbalta, or Duloxetine is a serotonin-norepinephrine reuptake inhibitor used to treat depression and neurological pain. Find out about the uses and risks. Duloxetine oral capsule is available as both a generic and brand-name drug. Brand names: Cymbalta and Irenka. Duloxetine only comes as a capsule you take by mouth. Note: This document contains side effect information about duloxetine. Some of the dosage forms listed on this page may not apply to the brand name Cymbalta. Cymbalta (duloxetine), a drug prescribed for neuropathic pain associated with diabetic peripheral neuropathy, depression, and anxiety. Side effect, dosage, and drug interaction information included. My doctor, who has extensive experience treating patients with Cymbalta for nerve pain, says that the most common (or effective) daily dosage for pain is anywhere between 60 - 120 mg per day. Cymbalta is the brand name for duloxetine, an antidepressant prescribed to treat the symptoms of depression. In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts.