Use Caution/Monitor. iloperidone increases levels of clonazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Iloperidone is a time-dependent CYP3A inhibitor and may lead to increased plasma levels of drugs predominantly eliminated by CYP3A4. Clonazepam is an anti-anxiety medication in the benzodiazepine family, the same family that includes diazepam , alprazolam , lorazepam , flurazepam (Dalmane), and others. Clonazepam and other benzodiazepines act by enhancing the effects of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter (a chemical that nerve cells use to communicate with each other) that inhibits brain. Clonazepam has been available in the United States since 1975, so doctors have plenty of experience with its use, but few large, well-controlled studies of its effectiveness have been performed. It has been shown to work for many different seizure types. Clonazepam (Oral Route) Print. Sections. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Proper Use. Drug information provided by: IBM Micromedex. Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this. Clonazepam, sold under the brand Klonopin among others, is a medication used to prevent and treat seizures, panic disorder, anxiety, and the movement disorder known as akathisia. It is a tranquilizer of the benzodiazepine class. It is taken by mouth. Effects begin within one hour and last between six and twelve hours. Common side effects include sleepiness, poor coordination, and agitation. Clonazepam may be habit forming. Do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Tell your doctor if you have ever drunk large amounts of alcohol, if you use or have ever used street drugs, or have overused prescription medications. Do not drink alcohol or use street drugs during your treatment. Clonazepam has a risk for abuse and addiction, which can lead to overdose and death. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems (especially. If you use clonazepam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Do not start or stop taking seizure medication during pregnancy without your doctor's advice. Having a seizure during pregnancy. Clonazepam can be successfully discontinued without any major withdrawal symptoms if the dose is reduced gradually. We recommend reducing the dosage of clonazepam after intermediate-term use by 0.25 mg/wk. Publication types Clinical Trial Comparative Study Research Support, Non-U.S. Gov't. Clonazepam is an inexpensive drug used to treat certain types of seizures.It is also used to treat panic disorder.This drug is slightly more popular than comparable drugs. It is available in brand and generic form. Generic clonazepam is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.