Learn about how triptans can be effective for migraine treatment as 60% of migraine sufferers who take triptans have their pain relieved within 2 hours. Imitrex (sumatriptan) is a selective serotonin receptor agonist used in oral, intranasal or injectable dosage form to treat migraine headaches. Imitrex is available as a generic drug. Treximet® (sumatriptan and naproxen sodium) is a selective 5-HT1B/1D receptor agonist and antiinflammatory indicated for the acute treatment of migraine, with or without aura, in adults and pediatric patients 12 years of age and older who have a clear migraine diagnosis. How to use Sumatriptan Succinate. Read the Patient Information Leaflet if available from your pharmacist before you start taking sumatriptan and each time you get a refill. Consumer drug information about the prescription drug sumatriptan ( Imitrex, Alsuma, Imitrex STATdose System, Sumavel DosePro) used to treat migraine and cluster headaches. Side effects, drug interactions, and pregnancy efficacy information is provided. If you inject Suboxone (buprenorphine and naloxone), it can be quite dangerous -- and even fatal. Before you shoot up with Suboxone, it is important to know that this medication contains naloxone, a drug that counteracts the effects of the opioid component of this drug when used via injection. Studies have not been done on Toradol and pregnancy in humans; however, previous animal studies suggest that it could possibly harm a fetus. Also, Toradol can complicate labor and delivery if taken during pregnancy. Imitrex (sumatriptan) for Migraine: It makes me crazy when I read that somebody waits until their headache is off the charts to take Imitrex. I have been suffering for over 25 years with migraines and then Imitrex came on the scene that was the end of the migraines. Sumatriptan is indicated for the acute treatment of migraine, with or without aura, and the acute treatment of cluster headache. Learn about side effects, drug interactions, dosages, warnings, and more. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger certain migraine symptoms.