Fluoxetine (Prozac) is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Prozac Weekly, the long-acting form approved for depression, can be used to replace daily doses of 20 mg. Because the medication stays in your system for so long, the first dose of Prozac Weekly should be taken one week after stopping Prozac 20 mg daily. A: A review of package inserts and medical literature shows that there are potential interactions between nortriptyline and the other medications you are taking. Nortriptyline comes as a capsule and an oral liquid to take by mouth. It is usually taken one to four times a day and may be taken with or without food. You may find that filling a 90-day supply will reduce your total cost for this prescription. As an added bonus, you'll make fewer trips to the pharmacy, saving you time and money. What other drugs will affect nortriptyline? Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking nortriptyline with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. A: It is always important to be aware of the medications you take and possible drug interactions. According the the prescribing information, Tikosyn and Prozac can interact and cause potentially. Prozac (fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Fluoxetine affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Defines the medication nortriptyline (Pamelor, Aventyl) a drug used to elevate the mood of patients with depression. Article includes descriptions, uses, drug interactions, and side effects. Pictures of Prozac (Fluoxetine Hcl), drug imprint information, side effects for the patient.