Prednisone has made my daughter have increased glucose levels and you may need to have those checked as the prednisone can cause you to have diabetic type symptoms which does definitely cause increased eye problems. I am not certain if the eye problems would be long term or if it will get better when you get off of medication. Despite prednisone’s many uses and effectiveness, it is known to cause many side effects. If prednisone must be taken for long periods of time, precautions must be taken to prevent complications such as gastrointestinal ulcers, diabetes, high blood pressure, hormonal problems, and osteoporosis. Prednisone is the only thing that makes my ulcers heal quickly. Of course the doctors don't want you to take it too often. When I have several ulcers I only need a few days of it to get better. Doctors give unbiased, trusted information on whether Advil can cause or treat Mouth Ulcers: Dr. Vallury on can ibuprofen cause mouth ulcers: All NSAIDs can cause ulcers. The risk of major GI issues with Ibuprofen is approximately 16%. Doctors give unbiased, trusted information on whether Advil can cause or treat Mouth Ulcers: Dr. Vallury on can ibuprofen cause mouth ulcers: All NSAIDs can. Can prednisone cause gastritis/ulcer. Took it for only 2 days and started getting stomach problems. Been off pred Took it for only 2 days and started getting stomach problems. Been off pred more Can prednisone cause gastritis/ulcer. Someone told me cheese & chocolate can cause mouth ulcers, pity about the chocolate! Hope you are all feeling good today, I am tired after a journey back from Wales on thursday, hoping tomorrow I will have a bit more go in me. Prednisone is a synthetic corticosteroid that reduces inflammation and suppresses the immune system. Prednisone is prescribed for a wide range of conditions, especially autoimmune diseases. You may want to look up Aphthous Ulcers. I have them ever since I started taking Adderall. It can be a variety of factors and it takes several for the eruption to occur. Lack of sleep, dry mouth, trauma, oral dyskinesia (a side effect of some meds), Iron deficiency, Vitamin B-12 deficiency and numerous other factors. I get them now once every six weeks or so. They hurt, I can't eat, I have. Gluten free and sugar free diet works for me! Palm 10 March 19: I am a 37 year old female and I have suffered from mouth ulcers for as long as I can remember. Summary. There is no Mouth sores reported by people who take Prednisone yet. This review analyzes which people have Mouth sores with Prednisone.