Can Hydrocodone cause Stomach Ulcers? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. However, if it’s most pain meds then you may have damaged or irritated your stomach lining. This could be especially possible if you’ve been taking the meds for a while. This could be especially possible if you’ve been taking the meds for a while. can anybody tell me what is the possibilties in taking hydrocodone (Lortab) and being pregnant?what are the chances in delievering a heathly baby if stopped taking this medicine at 8 months?Was taking a high does but cut back to only (1-2) 7.5mgs a day.Was taking up to (4-5) 10.650mgs a day.I know some people that their doctors gave them this medicine for headaches and very bad pain problems. Aspirin can affect the lining of your stomach and cause belly pain and other problems. Other pain relievers, like ibuprofen and naproxen , can lead to heartburn , irritation, and other stomach. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes). Stop taking Lortab and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. Hydrocodone can interfere with the diagnosis of many conditions that cause severe abdominal (stomach) pain. Like any other narcotic, hydrocodone can cause dizziness and drowsiness, and may increase the risk of falls in elderly people. I talked to my pain specialist at UofM (university of Michigan) about taking a vicodin on an empty stomach. I take them for numerous back, hip, spine and pelvic bone problems due to several reconstructive surgeries of my rt hip muscles and pelvic area that occurred 21 yrs ago, that no has worn down to almost nothing. There are a lot of different medications that you can take both by prescriptions, and over the counter drugs. I couldn't begin to tell you what to take, as the Dr. should be your first line of attck on the problem. The meds can do a whole lot of things to the lining of your stomach. So do consult with your Dr. Summary. Stomach pain is found among people who take Lortab, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Zometa, and have Birth control. Well, I had my wisdom teeth extracted five days ago, and was prescribed Hydrocodone, and an antibiotic, Amoxicillin. I can definitely say that not an hour after I took the Hydrocodone I started experiencing minor stomach pain, only in the upper abdominal area..