Common Questions and Answers about Vicodin and tylenol 3 vicodin I suffer from severe migraines and I am 16 weeks pregnant, I take 2 tylenol 3 ( tylenol with codiene) in the morning and 2 in the afternoon, they help, might want to check with your dr as they are a narcotic Best Answer: I have sort of the same problem Tyenol 3 makes me have a very upset stomach.I can take all the other medications and have after a big surgery.And when I told my Docter he said that was very commen.Maybe you can ask your neurologist since he seems to believe you.I know that my mom is allergic to. I suffer from severe migraines and I am 16 weeks pregnant, I take 2 tylenol 3 (tylenol with codiene) in the morning and 2 in the afternoon, they help, might want. I am in a lot of pain. I was prescribed Tylenol with Codeine,1- 2 tablets every 4-6 hours or Vicodin 1-2 tablets every 6 hours. The Vicodin is stronger, but wears off after 3 1/2-4 hours. Vicodin is stronger. The codeine in Tylenol 3, 30 milligrams per tablet, is not a good pain reliever in about 30% of the population. This may be the reason it is not working so well. You are comparing apples and oranges here and too many things come into play with a question like this. most of these meds have cns depressant/respiratory depressant qualities, side effects and adverse effects. Can I Take Vicodin And Tylenol 3 At The Same Time? I had my wisdom tooth removed and the pain is still unbearable. The vicodin isn't getting the pain completely gone. You can take regular Tylenol with them to augment the dose (you always want to ask for a lower dose Tylenol content for Percocet so you don't take too much), but you want to keep track of your. Vicodin contains Tylenol already, but at a less than therapeutic dose if you only take one tablet. It would not be an overdose to take one of each tablets together, but if 1 Vicodin would not be sufficient for pain relief, Dr would more likely prescribe a higher dose of Vicodin ( depending on the strength).