Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol is used to treat angina and hypertension (high blood pressure). Although they both treat high blood pressure and chest pain, these drugs aren’t interchangeable. They’re dosed differently. Metoprolol succinate comes as an extended-release oral tablet. Hypertension. Metoprolol Succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. Serious problems have been reported by some people who switched from the popular blood pressure medication Toprol XL to generic versions of metoprolol succinate extended-release, including dramatic increases blood pressure, heart rate, nausea, and dizziness. Read our review to learn more. 1 Answer - Posted in: amlodipine, blood pressure, metoprolol succinate er - Answer: Shouldn't take more than am hour, been on Propranolol for years. Abrupt discontinuation of any beta-adrenergic-blocking agent, including metoprolol, can result in the development of myocardial ischemia, myocardial infarction, ventricular arrhythmias, or severe hypertension, particularly in patients with preexisting cardiac disease. Learn about high blood pressure (hypertension) medications such as ACE inhibitors, beta blockers, diuretics, angiotensin II receptor blockers, calcium channel blockers, alpha blockers, alpha-2 receptor blockers, central agonists, peripheral adrenergic inhibitors, and vasodilators. Read about high blood pressure medication side effects. For most people, the first-choice medication for high blood pressure is a thiazide diuretic. For other people, a diuretic alone is not enough to control blood pressure. I am on Benicar and Metoprolol Succinate. Why would I need both when they are both for blood pressure? - Answered by a verified Doctor How to use Metoprolol Succinate. See also Warning section. Take this medication by mouth as directed by your doctor, usually once daily. Some brands of this medication (those containing metoprolol.