Answer. Benadryl is a medication that works by blocking the action of histamine, the mediator of common allergic reactions such as sneezing, itching, watery eyes, and runny nose. The relationship between Benadryl and high blood pressure arises from the effect the medication has on blood vessels and also its interaction with hypertension medications. High blood pressure, also called hypertension, is a major risk factor for heart disease. It has several causes including smoking, alcohol, caffeine, obesity, inactivity, emotional stress, heavy metal poisoning, birth control pills, and a diet high in sugar, fat, and salt. Les médecins définissent l’hypertension artérielle comme une lecture systolique supérieure à 140 mmHg (millimètre de mercure) et une lecture diastolique de 90 mmHg et plus. You can take Benadryl (diphenhydramine) if you have hypertension but with caution and only if your hypertension is controlled. Also let your doctor know that you are taking Benadryl so that he/she can monitor you. Diphenhydramine comes as a tablet, a rapidly disintegrating (dissolving) tablet, a capsule, a liquid-filled capsule, a dissolving strip, powder, and a liquid to take by mouth. Summary. Hypertension is found among people who take Benadryl, especially for people who are female, 60+ old , have been taking the drug for 1 month, also take medication Tylenol, and have Rheumatoid arthritis. Hypertension but most people are resorting to hypnotherapy the accumulation and care required for pregnant women shows the pressure will increase the chances of drugs known as anti-thrombotic agents which are around 120/80. Benadryl: La diphenhydramine appartient au groupe de médicaments appelés antihistaminiques. Les antihistaminiques s'utilisent pour traiter les symptômes causés par les allergies notamment une irritation oculaire et un larmoiement, des éternuements, un écoulement nasal, des éruptions et irritations cutanées.