The MIECs of ciprofloxacin, pazufloxacin, levofloxacin, moxifloxacin, garenoxacin, clarithromycin, and azithromycin were almost the same as their MICs, with MIEC 90 values of 0.015–0.06 μg/ml , although the MIEC of minocycline was relatively lower and that of rifampicin was higher than their respective MICs. Learn about the potential side effects of ciprofloxacin. Includes common and rare side effects information for consumers and healthcare professionals. Recommended Antimicrobial Agents for the Treatment and Postexposure Prophylaxis of Pertussis 2005 CDC Guidelines. Prepared by Tejpratap Tiwari, M.D. Bugs ‘N Drugs General Principles of Antimicrobial Therapy Hina N. Patel, Pharm.D., BCPS I. Basic Considerations a. Empiric treatment i. Site of infection Although several macrolide antibiotics are proarrhythmic and associated with an increased risk of sudden cardiac death, azithromycin is thought to have minimal cardiotoxicity. However, published. 500 mg PO on first day of therapy, followed by 250 mg PO once daily on days 2 to 5. Guidelines recommend azithromycin as a monotherapy option in previously healthy outpatients with no risk factors for drug-resistant S. pneumoniae and without therapy in the preceding 3 months. Before a genital ulcer is treated, an accurate diagnosis with appropriate testing is essential. Concomitant testing for human immunodeficiency virus (HIV) infection should be considered. Ciprofloxacin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Med Oral Patol Oral Cir Bucal. 2011 Nov 1;16 (7):e1031-5. Susceptibility of P. gingivalis to antibiotics Caution has been expressed about single-dose azithromycin 1 g inducing macrolide resistance in M genitalium, [49, 50, 51] despite ensuring compliance and successful treatment of cases of NGU in which test results are negative for Chlamydia, Mycoplasma, and Ureaplasma species.