Initially, 20 to 25 mg/kg caffeine citrate (equivalent to 10 to 12.5 mg/kg anhydrous caffeine base) IV for 1 dose; then after 24 hours, begin maintenance dose of 5 to 10 mg/kg/day IV caffeine citrate (2.5 to 5 mg/kg/day anhydrous caffeine base); adjust based on clinical response and, if necessary, caffeine blood concentrations. Antidepressant drug interactionsfi Revie Progress in Neurology and Psychiatry MayJune 21 23 potential drug–drug interaction, considering individ­ Grapefruit is a citrus fruit. People use the fruit, oil from the peel, and extracts from the seed as medicine. Grapefruit seed extract is processed from grapefruit seeds and pulp obtained as a byproduct from grapefruit juice production. Caffeine/ergotamine (trade name Cafergot) is the proprietary name of a medication consisting of ergotamine tartrate and caffeine. This combination is used for the treatment of headaches, such as migraine headache. Aspirin/paracetamol(acetaminophen)/caffeine is a combination drug for the treatment of pain, especially tension headache and migraine. It is sold in the US under the trade names Goody's Powder and Excedrin, although not all products sold under the Excedrin brand contain this combination. Look up a drug to see which other drugs it interacts with and how serious those interactions are. For the treatment of the symptom complex of tension headache, occasional migraine† and co-existing migraine† and tension-type headaches. NOTE: Extended and repeated use of acetaminophen; butalbital; caffeine is not recommended because of the potential for physical dependence. Low blood pressure after eating (postprandial hypotension. Black tea contains caffeine. Drinking beverages containing caffeine helps increase blood pressure in older people who have low blood pressure after eating. Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities. By Nancy Harris Bonk March 9, 2015 at 4:09 pm Moderator. Hi tbs448, Amitriptyline (also under the brand names Vanatrip, Elavil, Endep) and nortriptyline (brand names Pamelor, Aventyl HCl) are both tricyclic antidepressants that can be used for migraine prevention.